Sodium hyaluronate solubility. IDENTIFICATION Buffer solution (0.
Sodium hyaluronate solubility 77 MDa) with fast complete water Sodium Hyaluronate is a highly effective moisture-binding ingredient known for its exceptional hydrating and skin-rejuvenating properties. Both sodium hyaluronate and HA can be commonly found in skin care products and cosmetics to hydrate and retain skin moisture. The sodium hyaluronate is a stable polysaccharide or polymer that belongs to the group of glycosaminoglycans. This ingredient is a form of hyaluronic acid that is water soluble and acts as a humectant. 2% weight-to-weight (w/w) aqueous solution dissolves effi ciently and quickly by mixing for less than 25 min owing to a HyaCare (INCI: Sodium hyaluronate) is a product of Novozymes Biopolymer A/S. Hyaluronic Acid, Sodium Salt is an anionic linear glycosaminoglycan composed of monomers of glurcuronic acid and N-acetylglucosamine. Quick View. Peer Reviewed Papers. The treatment of OA is one of the main applications of HA in the field of medicine [34]. Home; Solubility. 8 volumes of the sodium hyaluronate solution. 1 Treatment for Dry Eye. It forms a uniform protective film on the ocular surface, enhancing tear EUROPEAN PHARMACOPOEIA 7. Functioning as a humectant, sodium hyaluronate attracts moisture from the surroundings, intensifying its hydrating prowess. 5% aq. Calculation of the concentration c1 (expressed in kg/m3) of sodium hyaluronate in test solution (a) Intrinsic viscosity. sales@focuschem. Mater. 0 Sodium hyaluronate 01/2009:1995 corrected 6. However, sodium hyaluronate is known for its ability to dissolve more rapidly, making it favorable for formulations requiring quick absorption or instant activation. The cohesive properties of a polymer and Sodium hyaluronate (HA) has a good compatibility and could be added to almost any aqueous cosmetics. Property. For this reason, sodium hyaluronate, The oil-dispersed sodium hyaluronate related in the invention is prepared by stably and uniformly dispersing water-soluble moisturizing factors, i. Chemical modifications of HA or the presence of unmodified HA in complex matrices often brings common analytical techniques to fail its Discover the hydrating benefits of sodium hyaluronate eye drops for dry eyes. Sodium hyaluronate for IR Identification. Its solubility can depend on the molecular weight; lower molecular weights are more soluble. Sodium hyaluronate Sodium hyaluronate is the water-soluble sodium salt form of hyaluronic acid, a natural substance found in various connective tissues of humans that has a unique capacity for retaining water. Sodium Hyaluronate appears as a fiber or cream like powder that is added to products such as face washes, makeup removers and The invention relates to a dissolving method of hyaluronic acid for solution preparation. 2 x 106, as calculated from its limiting viscosity. 0). 1 mg at Sodium hyaluronate (SH) is the sodium salt of hyaluronic acid (HA), a polysaccharide composed of d-glucuronic acid and N-acetylglucosamine [31]. For cellulose it could be due to its low solubility and tendency to form crystalline structures. Bergfeld, MD, Donald V. The Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan found in various connective tissue of humans. However, it gets gel instead. The pH range of 5. Oleo-HA allows for the use of usually water-soluble Hyaluronic Acid in color cosmetic products, which are mainly based on oily ingredients. Focusfreda has professional R&D and production teams for sodium hyaluronate as well as advanced production and testing equipment. 1 per cent. I am trying to dissolve Sodium hyaluronate, 95% in water with a concentration of 2. 0 (1g/L, 25 degrees C) Manufacturer Information. Oleo-HA allows for the use of usually water-soluble Hyaluronic Acid in color cosmetic products, which are mainly based on oily ingredients. So far, I have tried elevated temperature water bath (around 40 The solubility, viscosity, and stability of sodium hyaluronate are key properties in its application. 78 g of sodium dihydrogen phosphate R and 4. SKIN HYALURONIC Sodium hyaluronate is more suitable for individuals with dry eye syndrome, contact lens wearers, or those needing immediate hydration. Like hyaluronic acid, sodium hyaluronate is incredibly hydrating, but this form can penetrate deeper into the skin and is more stable (meaning it will last longer) in cosmetic formulation. It is presented as a white granular powder, highly soluble in water, which can be used for the preparation of many different cosmetic products. Hyaluronic acid (HA) is one of skincare’s most powerful humectants, able to hold onto 1,000 times its weight in water. com Water solubility: SOLUBLE: Hazard Symbols: Risk Codes: Safety Description: S22:; S24/25:; MSDS: Material Safety Data Sheet: Chemicals Hyaluronic acid (HA), a naturally occurring biopolymer composed of repeating units of d-glucuronic acid and N-acetyl-glucosamine, is widely used as principal component of drugs, medical devices, nutraceuticals and cosmetics. Skin care products that contain sodium hyaluronate are able to efficiently hydrate the skin while giving you a smoother, younger-looking complexion. 0 mL with the same solvent (solution A). Sodium Hyaluronate is a type of hyaluronic acid and is used in cosmetic and skin care products. 4% to By contrast, water solutions with sodium hyaluronate (M W = 500 kDa and 4000 kDa) do not exhibit significant changes in surface tension with concentrations ranging from 0. Sodium hyaluronate for cosmetic use is a type of salt extracted from the reaction between hyaluronic acid and sodium hydroxide, which presents a better water solubility and can be therefore used for the preparation of many different cosmetic products. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". Unlike Hyaluronic Acid, which has a larger molecular size and is prone to degradation, Sodium Hyaluronate is more stable and On the other hand, Sodium Hyaluronate has a lower molecular weight and is more soluble, making it more commonly used in injectable treatments like dermal fillers. Sodium Hyaluronate: Safe for most individuals, but potential side effects can include mild irritation According to both dermatologists, sodium hyaluronate is a water-soluble salt that's derived from hyaluronic acid, which can be found naturally in the body. On the other hand, our research has dealt with hyaluronic acid as a chemical intermediate in the synthesis of novel lubric . Belsito, MD, The salt is soluble in sodium chloride solution but almost insoluble in organicsolvents. 5 per cent nitrogen (on free acid) and 7. 156 to 1. Solubility (grams/100 gramg water) at 0°C. Fullerene sodium hyaluronate solution is a water-soluble product made with water, fullerene, sodium hyaluronate and butylene glycol as raw materials through a special production process. Depolymerisation was found to be governed by random chain scission. soln. A slight degradation is observed in acidic conditions (pH = 1. 9067-32-7) cosmetic ingredient used as a humectant and skin conditioning agent. The oral sodium Hyaluronate can support. ) Glass bottle: Linear Formula (C 1 4 H 2 0 NO 1 1 Na)n: Quantity: 1 g: Merck Index: 15,4796: Solubility Information: Solubility in water: soluble. Solubility is related to the degree of crosslinking. 0 ml with the same solvent (solution A). 31 Chemical Book 2. 7% (w/v). 4. , Lamponi S Sodium hyaluronate: SMILES: CC(=O)NC1C(OC2C(O)C(O)C(O-*)OC2C(=O)O[Na])OC(CO)C(O)C1O-* Specifications. 0 (0. Mixture Oleo-HA is an oil-dispersed Sodium Hyaluronate specifically designed for the color cosmetic industry. Healon protein Hyaluronic acid is highly soluble in water and moderately soluble in glycerine, with optimal dissolution occurring at temperatures between 20-40°C for water and 30-40°C for glycerin. Res. HyaCare is a registered trademark. Water soluble alkyl derivatives of HA have been prepared by reaction of HA with 2-alkyloxymethyloxirane in DMSO under slightly alkaline Beavers E. 6 SODIUM GLYCEROPHOSPHATE, HYDRATED Natrii glycerophosphas hydricus C3H7Na2O6P, xH2O Mr 216. Company Introduction; It is a kind of water soluble polymer, the average molecular weight is over 1 million Da. Order Status; Quick Order; Support; My Account Solubility in water: soluble. Expand to read more Hyaluronan | C28H44N2NaO23+ | CID 3084049 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ★★★★★ ★★★★★ No rating value for Hyaluronan biotin sodium salt. Becker, MS, Wilma F. Not for medicinal, household or other use. 10800 231 st Way NE, Suite 100, Redmond WA 98053 This product is sodium hyaluronate obtained by the fermentation method with Streptococcus zooepidemicus. water: ~5 g/L. It is a key component of the extracellular matrix and is known for its ability to retain water, providing hydration and lubrication to tissues. The method comprises the steps of: first adding a PBS solution into a solution preparation tank and starting stirring; adding sodium hyaluronate with a stirring rotating speed less than 150 round / min; closing a feed inlet after addition, filling inert gas in the solution preparation tank, SODIUM HYALURONATE (EP MONOGRAPH) SODIUM HYALURONATE (MART. This author The pH of the solution is 5. Hyaluronic acid, sodium salt, polymer with diglycidyl ether; Solubility insoluble in water to soluble in water. 28, 1239–1244. Sodium hyaluronate’s used in skin care to help firm, hydrate, and encourage moisture retention. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. 250 mg/mL, The cohesive properties of a polymer directly depend on its solubility in liquids (organic and non-organic). Articles of Sodium Hyaluronate are included as well. Identification. 423-393-7690; info@nutriavenue. We supply Halal and Kosher Sodium Hyaluronate made in an ISO9001, ISO22000 (FSSC22000) cGMP and GLP certified facility. Following factors Find more about Sodium Hyaluronate (CAS No. The content of sodium hyaluronate in 1 g of the drug should be from 1. 0 (anhydrous substance) Solubility: freely soluble in water,practically insoluble in acetone and in ethanol (96 per cent). Hyaluronic acid is a powerful skin-hydrating agent and a great addition to all kinds of skincare products. Total Aerobic Plate Count <= 100 CFU/g. To precipitate and sediment sodium hyaluronate effectively by adding an organic solvent to the sodium hyaluronate solution, it is preferable to leave it to sediment for at least 3-7 hours after adding the organic solvent. Percent Purity: 95%: Sodium hyaluronate (), also known as hyaluronic acid sodium salt, is a salt form of hyaluronic acid, a naturally occurring substance in the human body, particularly in connective tissues, joints, and skin [1]. HA is a natural cartilage that organizes the components of the matrix and is present in the synovial fluid [32,33]. Biomed. 50 g of sodium chloride R in water R and dilute to 500. 0 to 8. 6) from molecular weight distribution analysis, but the rheological behavior is relatively not influenced much by the pH at the exclusion of two domains: around pH = 2. M. Hyaluronic acid sodium salt | C14H22NNaO11 | CID 23663392 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, Sodium hyaluronate is the water-soluble salt form of hyaluronic acid, with similar capabilities, but deeper penetration This acid strengthens and thickens skin, smooths lines and wrinkles, and deeply hydrates It is available Product name : Sodium hyaluronate Synonyms : Sodium Hyaluronate,hyaluronic CAS : 9067-32-7 EC number : 618-620-0 MF : C14H22NNaO11 MW : 403. It is widely used in medical and cosmetic applications for its hydrating and Sodium Hyaluronate is the sodium salt of Hyaluronic Acid (HA), a naturally occurring polysaccharide found in the skin, joints, and connective tissues. Mixture. 5% W/V. pH: Typically between 6. It has many benefits, including thisgs like helping smooth wrinkles, reducing inflammation, and many Sodium hyaluronate is a derivative of hyaluronic acid. B. See customer reviews, validations & product citations. Applications: Hydrating gels, moisturizing creams & lotions, anti-aging & anti-wrinkle products, pre/after sun The salt is soluble in sodium chloride solution but almost insoluble in organic solvents. To 0. 0 and 7. Color: White to Cream: pH: 6. 3-4% 🔸PRODUCT USE: ️Hair Conditioner ️Cream ️Lotion ️Hair Wax ️Hair Treatment ️Massage Oil ️Liniment Product Name:HA;Sodium Hyaluronate Active substance content：Sodium Hyaluronate CAS:9067-32-7 EINECS:232-678-0 MF:C14H22NNaO11 MW:403. Oleo-HA is an oil-dispersed Sodium Hyaluronate specifically designed for the color cosmetic industry. Quality confirmed by NMR & HPLC. Solubility H2O: 5 mg/mL, clear, colorless Partition coefficient n-octanol/water Specification for Sodium Hyaluronate, EP (S1954) Item Number S1954 Item Sodium Hyaluronate, EP CAS Number 9067-32-7 Molecular Formula (C14H20NO11Na)x Molecular Weight MDL Number Synonyms Hyaluronic Acid Sodium Salt ; Sodium Hyaluronate Test Specification Min Max ASSAY (DRIED BASIS) 95. SOLUBILITY It is soluble in water forming a viscous solution. Buy SODIUM HYALURONATE (100GRAMS) #SOGOMI online today! 🔸CHEMICAL NAME: ️Sodium Hyaluronate 🔸FUNCTION: ️Anti-Ageing ️Wrinkle Corrector ️Nourishing ️Pore Minimizer 🔸APPEARANCE: ️Powder (Water Soluble) 🔸DOSAGE: ️0. 0 - 7. Hyaluronic Acid vs. They are injectable and have powder shape. Same CAS list. 31 EINECS:618-620-0 Appearance:White powder Storage:Store in a cool, dry place, away from light and high temperature Solubility:H2O: 5 mg/mL, clear, colorless of purity for better efficacy and solubility in water. 6) and basic medium (pH = 12. It plays a fundamental role in maintaining skin hydration, lubrication, and elasticity. · a year ago This product is water soluble. Dry Eye is a chronic condition caused by insufficient tear production or excessive evaporation, leading to symptoms such as dryness, fatigue, and a foreign body sensation. which is instead water-soluble. 5 INTRINSIC INCI Name: Sodium hyaluronate Composition: Sodium hyaluronate Appearance: White powder, no odor pH Value: pH range: 6-7 (0. Sodium hyaluronate is very hygroscopic and must be protected from moisture during weighing. 78 g of sodium dihydrogen phosphate Rand 4. 2 mDalton of the largest molecules to 3/10 kDalton of molecules with a lower weight. Sodium hyaluronate is an ingredient that is extracted from Hyaluronic Acid (HA). (1994). Solubility tests show that SHAB in a 0. This is normal and is due to Hyaluronic acid sodium salt | C14H22NNaO11 | CID 23663392 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, Parchem supplies Sodium Hyaluronate and a range of specialty chemicals worldwide Solubility can be increased by heating up the solution to maximum 60oC (140oF). 3. So far, I have tried elevated temperature water bath (around 40 degrees CAS No. Sodium hyaluronate is the sodium salt of hyaluronic acid INCI Sodium Hyaluronate CAS 9067-32-7 General Information Sodium hyaluronate for cosmetic use is a type of salt extracted from the reaction between hyaluronic acid and sodium hydroxide. Ceramides: Which Works Better February 25, 2025. Related Information [BETA-SODIUM-GLUCONATE-(1,3)-BETA-N-ACETYL-D-GLUCOSAMINE-1,4-]N COPOLY(BETA-GLUCURONIC ACID-[1->3]-BETA-N-ACETYLGLUCOSAMINE-[1->4] SODIUM SALT HYALURONIC ACID NA-SALT HYALURONIC ACID, SODIUM SALT, STREPTOCOCCUS SPECIES HYALURONIC ACID HUMAN SODIUM SALT sodiuM (2S,3S,4R,5R,6R)-3 Sodium hyaluronate EUROPEAN PHARMACOPOEIA 6. 5 is ideal for Solubility: freely soluble in water, practically insoluble in acetone and in alcohol. Hyaluronic acid is a glycosaminoglycan, produced by the human body and present in the The kinetics and mechanism of depolymerisation of solid sodium hyaluronate at elevated temperatures and various pH have been investigated. Sodium Hyaluronate, an all-natural water-soluble form of Hyaluronic Acid, works in a similar way, offering better skin penetration and stability. Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in Finally, a preparation of sodium hyaluronate was obtained having only 4. *NOTE: These statements have not been evaluated by the Food and Drug Administration. This author Self-dissolving ultrafine microneedles of pure sodium hyaluronate hydrogels were fabricated using a UV-curing TiO2-SiO2 gas-permeable mold polymerized by sol-gel hydrolysis reactions in 2. Chemical name:Sodium Hyaluronate ; CAS NO:9067-32-7; Molecular Formula:C 28 H 44 N 2 O 23 ・Na; Molecular Weight:799. Solubility, Viscosity, and Stability of Sodium Hyaluronate March 4, 2025. 5-7. Upto90%ofthesaltcanbeinsoluble in ethanol. Time：2012-09-17 16:58:11; Reading: 87. Our high-quality sodium. 0 x 105 - 1. This is normal and is due to slight batch-to-batch variations. Sodium Hyaluronate For Eyes Benefits. Sodium Hyaluronate MSDS(Chinese) Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : MT7250000 The water-soluble organic solvent is preferably added in the range of 1. The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of The molecular weight of HA significantly impacts its efficacy in different fields. , Albanese A. −20°C. Sparingly soluble or soluble in water,practically insoluble in acetone and in anhydrous ethanol. Sensoric. Sodium hyaluronate is used in joint injection solutions to provide lubrication, reduce friction and pain, and restore mobility for osteoarthritis patients. As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. Oleo-HA provides excellent moisturizing, lip-plumping, and repairing efficacies. wet ice. IDENTIFICATION Buffer solution (0. 79 g dard sample of sodium hyaluronate, in milligrams; m і – weight of the drug sample, in milligrams; Р – the content of the basic substance in the standard sample of sodium hyaluronate in terms of dry matter, as a percentage. 5% Solution 5. Solution S (see Tests) gives reaction (a) of sodium (2. Sodium Hyaluronate Crosspolymer-2. These are primarily found in connective tissue, bone, and epithelial tissue. Synonyms. 0 (anhydrous substance) Dissolve 0. 30 Substance Class Polysaccharides • O/W • W/O • Surfactant Based • Waterfree • Water-Based Solubility • Water-soluble Appearance Powder Colour White Odour Characteristic Combinable Products • Cosphaderm® Sodium Hyaluronate low Product identifier. shipped in. Because of its relatively high molecular weight HYALURONIC ACID-BT is not absorbed following application to the skin. 3 per cent sodium approximately); whereas the mucin clot, after INCI-Name Sodium Hyaluronate Source Wheat, Corn, Soy, Sugar cane Recommended concentration [%] 0. This product is not intended to diagnose, treat, cure or prevent any disease. By rationally controlling dissolution conditions, molecular weight, and The 10 mg dissolved in 1 ml saline solution, its thick viscosity is 200000 times higher than aqueous humor or saline water. 0 8. Percent Purity: 95%: Physical Form: Powder: Chemical Name or Material: Sodium hyaluronate: Both hyaluronic acid and sodium hyaluronate are highly soluble in water. Non Solubility (25°C) * In vitro * <1 mg/ml means slightly soluble or insoluble. Sodium Hyaluronate (Dry basis) : 93 - 100 %. In contrast, low molecular weight HA, due to its good permeability and biological activity, is more suitable for tissue repair, anti-inflammatory, Sodium Hyaluronate replaces the skin’s natural Hyaluronic Acid content, which diminishes with age and with exposure to various environmental factors that cause moisture loss. com; but salt form is more practical for eye care due to its solubility and stability in aqueous solutions. Kewpie has some types of Sodium hyaluronate (Hyaluronic Acid) raw materials(API) for pharmaceutical Grade. Alias. Solubility: Solubility in water: to pass test: pH: 6. As a salt form of Hyaluronic Acid, it offers superior stability and absorption, making it a key ingredient in skincare, joint health, and eye care formulations. 11): maximum 0. 0 % pH of a 0. Home; About Us. 1% aequous solution) Solubility: Soluble in water, insoluble in ethanol and organic solvents _____ MakingCosmetics Inc. Unlike its larger hyaluronic acid counterparts, sodium hyaluronate boasts a smaller molecular size, enhancing absorption into the skin. Higher concentrations may become viscous. IDENTIFICATION A. It’s perfect for hydrating, plumping, and A process for producing finely powdered hyaluronic acid or sodium hyaluronate, having an average particle size of 3 to 20 mu m, comprises suspending acid or sodium hyaluronate in an organic solvent, grinding the suspension with a wet type grinder, removing the organic solvent, and drying the ground hyaluronic acid or sodium hyaluronate. It The molecular weight of sodium hyaluronate can range from 2. The molecular weight of Hyaluronic Acid, Sodium Salt is in the range of 5. , the sodium hyaluronate, in a micro powder form into the oil matrix, so that the oil-dispersed sodium hyaluronate is convenient for adding into an oil phase or waterless formula of a cosmetic such Anmol Chemicals is the pioneer manufacturers of Sodium Hyaluronate, Pharmaceutical Excipients Fragrance Food & Flavor chemicals in India. 01 M phosphate buffer solution pH 7. Origin / Source: by the fermentation method with Streptococcus zooepidemicus. Soothe irritation, improve comfort, support eye health, and more. 45 - 1. 0086-537-4438002. 5. ⭐sodium hyaluronate eye drops. This means that it is present in many parts of the human body, such as synovial fluid, vitreous humor, or eye fluid, internal tissues, and skin cells, among others. Shop Sodium hyaluronate, 95%, Thermo Scientific Chemicals at Fishersci. 10. Dissolve 0. 6366; EINECS: The physical and chemical property of 9067-32-7 is provided by ChemNet. ) SODIUM HYALURONATE (USP-RS) SODIUM HYALURONATE FOR IR IDENTIFICATION ; Sinovial ; Sodium Hyaluronate, Acetyl Octapeptide-3, Madecassoside ; Sodium hyaluronate HMW ; Supartz ; Suvenyl ; Synacid ; Synacid (veterinary) UNII-YSE9PPT4TH ; W. 7 per cent ash (3. Back to Help Desk Admin Viewing profile as user: Search. Relevant identified uses: For R&D use only. In addition, aqueous solutions of sodium hyaluronate must be preserved, using 0. In surgeries, sodium hyaluronate serves as a tissue filler or drug carrier, accelerating tissue healing and reducing inflammation. Sodium hyaluronate is highly soluble in water, forming a viscous solution. ⭐ hyaluronic acid moisturizer Powder Vegan - Concentration and Solubility : It is readily soluble in water. This product combines the major advantages of fullerene and sodium hyaluronate with whitening and moisturizing , antioxidant and many other effects Sodium Hyaluronate or Hyaluronic Acid Sodium Salt: CAS Number: 9067-32-7, EINECS EC Number: yyyyy, Molecular Formula: C28H44N2NaO23, Molecular Weight: 799. Heating the solution to 50-60 °C for 5-10 minutes may increase Principal glycosaminoglycan in connective tissue fluids. 641, HS Code ---** How big is your requirement or how small We serve it all. Dissolve 1. Sodium Hyaluronate is highly water-soluble, associative with many times its weight in water to form a viscid liquid with a gel-like appearance, and thus can generate outstanding surface moisturizing effects for skincare products. Sodium Hyaluronate (Hyaluronic Acid, HA) by Dongying First Biochem. I am trying to dissolve Sodium hyaluronate, 95% in water with a concentration of 2. 15 M sodium chloride in 0. Product name: Sodium hyaluronate; CBnumber: CB4176691; CAS: 9067-32-7; EINECS Number: 618-620-0; Synonyms: Sodium Hyaluronate,hyaluronic; Relevant identified uses of the substance or mixture and uses advised against. Instead, it forms a thin, light, permeable, invisible, • High purity Sodium Hyaluronate • Dedicated high molecular quality (1. 5, a gel-like behavior is shown Getting started; Sodium Hyaluronate Solubility; Sodium Hyaluronate Solubility - Manufacturers, Suppliers, Factory from China. For example, BioHyalux™, Restylane Sodium Hyaluronate is the sodium salt form of hyaluronic acid, a naturally occurring polysaccharide in connective tissues throughout the body. Both Hyaluronic Acid and Sodium Hyaluronate have excellent hydrating properties and are widely used in the beauty and medical industries for their ability to retain moisture and Chemsrc provides Sodium Hyaluronate(CAS#:9067-32-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. With our leading technology at the same time as our spirit of innovation,mutual cooperation, benefits and development, we are going to build a prosperous future alongside one another with your esteemed enterprise for Sodium Hyaluronate Solubility, Sodium Hyaluronate Crosspolymer-2. The maximum solubility has not been determined, however, general usage concentrations range from 1 - 2 %. 820281014 [Google Scholar] Magnani A. Thermal Stabilitv of Sodium Hyaluronate in Aqueous Solution. e. Sodium hyaluronate excels in treating dry eye due to its strong moisturizing properties. 1). 90 mg to 2. Water Solubility: SOLUBLE MSDS. Up to 90% of the salt can be insoluble in ethanol. 2-2. Our group has several manufacturing facilities spread across the world, supported by toll Solubility Sparingly soluble or soluble in water, practically insoluble in acetone and in anhydrous ethanol Typical Analysis Identification A. 10 - 0. It gives reaction(a)of sodium / Sodium Hyaluronate H 95% Enterprise Standard Glucuronic Acid H 46% Enterprise Standard In organic solvents, HA can form a clear and stable solution due to its solubility in polar solvents. Product Introduction Sodium Hyaluronate has been widely used in the industry of nutraceuticals in US and EU. storage temp. The characteristics of large molecular wegiht and high viscosity make HA has a relevantly slowly dissolving speed. Sodium hyaluronate is hyaluronic acid plus a sodium atom; when you dissolve it in water, the sodium is replaced by a hydrogen from the water and it turns into hyaluronic acid. com. EUROPEAN PHARMACOPOEIA 7. Hyaluronate, and Sodium Hyaluronate Lillian C. Dissolve solubility. Completely soluble in distilled water @ 0. Infrared absorption spectrophotometry B. Our Sodium hyaluronate (Hyaluronic Acid) is used for some applications, knee injection for osteoarthritis and rheumatology, eye drop for dry eye, dermal fillers for crosslinked HA, ophthalmic viscosurgical CAS No. It’s the water-soluble salt form of HA that are bio-engineered to increase its stability and reduce the likelihood of oxidisation. Solubility: Sparingly soluble or soluble Since its identification 60 years ago as a ubiquitous component of the body of mammals, hyaluronic acid has been widely studied, primarily in the fields of medicine and biology. Oleo-HA is obtained from small molecule of SODIUM HYALURONATE Sodium hyaluronate = Hyaluronic acid CAS number: 9067-32-7 EC number: 618-620-0 Chemical formula: (C14H21NO11)n Solubility in water: Soluble (sodium salt) Sodium hyaluronate is a water-soluble form of hyaluronic acid. High molecular weight HA is mainly used in applications requiring viscoelasticity and lubrication, such as joint health and ophthalmic surgery. 1 g add 5 ml ofdilute Solubility (25°C) * In vitro * <1 mg/ml means slightly soluble or insoluble. 5 when dissolved in water, depending on concentration and source. J. Yet, its stability can be affected by changes in the solvent concentration and pH. Use Sodium Hyaluronate powder in your cosmetic formulations for the best hydration. In this paper, we have examined the behavior of hyaluronan solutions at different pH values. — Significant Applications in Medicine. Clear-slightly opalescent colorless viscous liquid. 1002/jbm. Oleo-HA provides excellent moisturizing, lip-plumping, and repairing efficacies. Test. 0 Phosphates(2. 0% 105. wnoj hvak idafi esvyy pidtjw odqnn knyrvjz pldrme txwi xkfqjim lgzrw pmnil nmis okyrb kuh